Solubility of the Proteinogenic α-Amino Acids in Water, Ethanol, and Ethanol–Water Mixtures

Solubility of the Proteinogenic α-Amino Acids in Water, Ethanol, and Ethanol–Water Mixtures

The addition of organic solvents to α-amino acids in aqueous solution could be an effective method in crystallization. We reviewed the available data on the solubility of α-amino acids in water, water-ethanol mixtures, and ethanol at 298.15 K and 0.1 MPa. The solubility of l-alanine, l-proline, l-arginine, l-cysteine, and l-lysine in water and ethanol mixtures and the solubility of l-alanine, l...

solubility of atenolol in ethanol + water mixtures at different temperatures

performance of solubility models for prediction of acetaminophen solubility in binary and ternary solvent mixtures of ethanol, water and glycerin

The Solubility of Amino Acids and Two Glycine Peptides in Aqueous Ethanol and Dioxane Solutions

The solubilities of amino acids, diglycine, and triglycine have been measured in water and aqueous ethanol as well as dioxane solutions. Free energies of transfer of amino acid side chains and backbone peptide units from water to ethanol and dioxane solutions have been calculated from these data. The results show the similarity between the ‘effects of ethanol and dioxane on the stability of tho...

On the temperature coefficient of the solubility of some glycyl peptides in water-ethanol mixtures.

The solubility of glycine, diglycine, and triglycine was investigated in water-ethanol mixtures (20% and 50% ethanol) as a function of the temperature. The transfer free energy, @go,,,, for the peptide group was evaluated and the separate enthalpy and entropy components of the transfer process were determined. In 20% ethanol solutions, the hypothesis of additivity of the contribution of various...